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SNAP23 Rabbit pAb (bs-11362R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-11362R
英文名称 SNAP23 Rabbit pAb
中文名称 突触相关蛋白23抗体
别    名 SNAP 23; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23_HUMAN; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Synaptosomal associated protein; Synaptosomal-associated protein 23; Vesicle membrane fusion protein SNAP 23; Vesicle membrane fusion protein SNAP23; Vesicle-membrane fusion protein SNAP-23; HsT17016.  
研究领域 神经生物学  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 23 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNAP23: 101-200/211 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Function:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Subunit:
Homotetramer (via coiled-coil domain), also forms heterotetramers with STX4 and VAMP3. Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A.

Subcellular Location:
Cell membrane. Cell membrane. Cell junction > synapse > synaptosome. Mainly localized to the plasma membrane.

Tissue Specificity:
Ubiquitous. Highest levels where found in placenta.

Similarity:
Belongs to the SNAP-25 family.
Contains 2 t-SNARE coiled-coil homology domains.

SWISS:
O00161

Gene ID:
8773

Database links:

Entrez Gene: 453365 Chimpanzee

Entrez Gene: 522423 Cow

Entrez Gene: 478268 Dog

Entrez Gene: 101141000 Gorilla

Entrez Gene: 8773 Human

Entrez Gene: 20619 Mouse

Entrez Gene: 100174679 Orangutan

Entrez Gene: 64630 Rat

Omim: 602534 Human

SwissProt: O00161 Human

SwissProt: O09044 Mouse

SwissProt: O70377 Rat

Unigene: 511149 Human

Unigene: 245715 Mouse

Unigene: 14789 Rat



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