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Rabbit Anti-PTP zeta  antibody (bs-11327R)  
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-11327R
英文名称 Rabbit Anti-PTP zeta  antibody
中文名称 磷酸蛋白聚糖PTPRZ抗体
别    名 Phosphacan; 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; protein tyrosine phosphatase receptor type Z1; Protein tyrosine phosphatase receptor type Z polypeptide 2; Protein tyrosine phosphatase, receptor type, Z polypeptide 1; Protein tyrosine phosphatase, receptor type, zeta polypeptide 1; PTP-ZETA; PTP18; PTPRZ; PTPRZ1; PTPZ; R PTP zeta 2; R-PTP-zeta; Receptor type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta; RPTP-BETA; RPTPB; RPTPbeta; PTPRZ_HUMAN; PTPζ.  
研究领域 细胞生物  神经生物学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,Mouse (predicted: Rat)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 251kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTP zeta: 421-520/2315 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

Function:
May be involved in the regulation of specific developmental processes in the CNS.

Subunit:
The carbonic-anhydrase like domain binds to contactin (By similarity).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
Contains 1 alpha-carbonic anhydrase domain.
Contains 1 fibronectin type-III domain.
Contains 2 tyrosine-protein phosphatase domains.

SWISS:
P23471

Gene ID:
5803

Database links:

Entrez Gene: 5803 Human

Entrez Gene: 19283 Mouse

Entrez Gene: 25613 Rat

Omim: 176891 Human

SwissProt: P23471 Human

SwissProt: Q62656 Rat

Unigene: 489824 Human

Unigene: 10088 Rat



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