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Rabbit Anti-lipocalin 1/LCN1  antibody (bs-11286R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-11286R
英文名称 Rabbit Anti-lipocalin 1/LCN1  antibody
中文名称 脂质运载蛋白1抗体
别    名 LCN1; LCN1_HUMAN; Lipocalin 1 (protein migrating faster than albumin, tear prealbumin); Lipocalin 1 like 2; Lipocalin-1; lipocalin 1; PMFA; Tear lipocalin; Tear prealbumin; Tlc; TP antibody VEG protein; VEGP; Von Ebner gland protein.  
Specific References  (1)     |     bs-11286R has been referenced in 1 publications.
[IF=5.123] Jia, W. et al. Elimination terminal fixed region screening and high-throughput kinetic determination of aptamer for lipocalin-1 by surface plasmon resonance imaging, (2018) Analytica Chimica Acta  SPRi chip ;  
研究领域 细胞生物  神经生物学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 17kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human lipocalin 1: 101-176/176 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Lipocalin-1 is a secretory protein that is highly expressed in fluids covering epithelial surfaces such as tears and respiratory secretions. This major lipid-binding protein in tears is also called tear lipocalin (TL) and von Ebner’s gland protein (VEG), as it is also a major secretion of these lingual salivary glands. In addition to lacrimal glands and lingual glands, Lipocalin-1 is secreted by nasal mucosal glands, secretory glands of the tracheobronchial tract, sweat glands, mammary glands, adrenal gland, prostate, thymus, testis and corticotrophs of the pituitary gland. Specifically, Lipocalin-1 functions to stabilize the lipid film of human tear fluid by removing harmful lipids from the human corneal surface and delivering them to the aqueous phase of tears. Lipocalin-1 may also function as a transporter of hydrophobic molecules such as bitter substances on the tongue.

Function:
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.

Subunit:
Homodimer. Binds to LMBR1L which may mediate its endocytosis.

Subcellular Location:
Secreted.

Tissue Specificity:
Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.

Similarity:
Belongs to the calycin superfamily. Lipocalin family.

SWISS:
P31025

Gene ID:
3933

Database links:

Entrez Gene: 3933 Human

Omim: 151675 Human

SwissProt: P31025 Human

Unigene: 530311 Human



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