产品编号 | bs-8717R |
英文名称 | SLC30A3 Rabbit pAb |
中文名称 | 溶质载体锌转运3抗体 |
别 名 | SLC30A3; Solute carrier family 30(zinc transporter), member 3; Solute carrier family 30 member 3; Zinc transporter 3; Zinc transporter ZnT 3; ZnT-3; ZNT3; ZNT3_HUMAN; OTTHUMP00000201041. |
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Specific References (1) | bs-8717R has been referenced in 1 publications.
[IF=7.419] Jinfeng Shang. et al. Chrysin protects against cerebral ischemia-reperfusion injury in hippocampus via restraining oxidative stress and transition elements. BIOMED PHARMACOTHER. 2023 May;161:114534 IHC ; Rat.
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研究领域 | 神经生物学 转录调节因子 通道蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse,Rat (predicted: Human,Pig,Cow,Dog) |
产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 42 kDa |
检测分子量 | |
细胞定位 | 细胞浆 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC30A3/ZNT3: 21-120/388 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-3 mediates the uptake of zinc into vesicles in brain and testis. Function: Involved in accumulation of zinc in synaptic vesicles. Subunit: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein (Probable). Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. SWISS: Q99726 Gene ID: 7781 Database links: Entrez Gene: 7781 Human Entrez Gene: 22784 Mouse Omim: 602878 Human SwissProt: Q99726 Human SwissProt: P97441 Mouse Unigene: 467981 Human Unigene: 1396 Mouse Unigene: 9297 Rat |
产品图片 |
Positive sample:Paraformaldehyde-fixed, paraffin embedded (mouse brain);
Negative sample:Paraformaldehyde-fixed, paraffin embedded (rat intestine);
Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3%
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |