扫码关注公众号           扫码咨询技术支持           扫码咨询技术服务
  
客服热线:400-901-9800  客服QQ:4009019800  技术答疑  技术支持  质量反馈  人才招聘  关于我们  联系我们
产品中心-北京博奥森生物技术有限公司
首页 > 产品中心 > 一抗 > 产品信息
Rabbit Anti-SCUBE1  antibody (bs-9903R)  
~~~促销代码KT202411~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-9903R
英文名称 Rabbit Anti-SCUBE1  antibody
中文名称 新型血小板相关血管内皮分泌蛋白SCUBE1抗体
别    名 SCUB1_HUMAN; SCUBE 1; SCUBE1; Signal peptide, CUB and EGF-like domain-containing protein 1.  
研究领域 心血管  内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 105kDa
细胞定位 细胞膜 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCUBE1: 451-550/988 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.

Function:
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.

Subunit:
Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3.

Subcellular Location:
Secreted. Cell membrane.

Tissue Specificity:
Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.

Post-translational modifications:
N-glycosylated.
Could be proteolytically cleaved to release a smaller active fragment.

Similarity:
Contains 1 CUB domain.
Contains 9 EGF-like domains.

SWISS:
Q8IWY4

Gene ID:
80274

Database links:

Entrez Gene: 80274 Human

Entrez Gene: 64706 Mouse

Entrez Gene: 315174 Rat

Omim: 611746 Human

SwissProt: Q8IWY4 Human

SwissProt: Q6NZL8 Mouse

Unigene: 133995 Human

Unigene: 40393 Mouse



版权所有 2004-2026 www.bioss.com.cn 北京博奥森生物技术有限公司
通过国际质量管理体系ISO 9001:2015 GB/T 19001-2016    证书编号: 00124Q34771R2M/1100
通过国际医疗器械-质量管理体系ISO 13485:2016 GB/T 42061-2022    证书编号: CQC24QY10047R0M/1100
京ICP备05066980号-1         京公网安备110107000727号