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TXNDC9 Rabbit pAb (bs-9429R)  
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产品编号 bs-9429R
英文名称 TXNDC9 Rabbit pAb
中文名称 胚胎干细胞相关蛋白TXNDC9抗体
别    名 Thioredoxin domain containing 9; APACD; ATP binding protein associated with cell differentiation; ATP-binding protein associated with cell differentiation; ES cell related protein; PHLP3; Phosducin like protein 3; Protein 1 4; Protein 1-4; Thioredoxin domain containing 9; Thioredoxin domain containing protein 9; Thioredoxin domain-containing protein 9; TXND9_HUMAN; TXNDC9; TXNDC9 protein.  
研究领域 细胞生物  免疫学  干细胞  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 26 kDa
检测分子量
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TXNDC9: 151-226/226 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Thioredoxins comprise a family of small proteins that, by catalyzing the oxidation of disulfide bonds, participate in redox reactions throughout the cell. Proteins that contain thioredoxin domains do not necessarily convey the oxidative properties of thioredoxins, but generally function as disulfide isomerases that enzymatically rearrange disulfide bonds found in various proteins. TXNDC9 (thioredoxin domain-containing protein 9), also known as APACD (ATP-binding protein associated with cell differentiation), is a 226 amino acid protein that contains one thioredoxin domain and may be involved in cell differentiation events. The gene encoding TXNDC9 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr鰉 syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Subunit:
Forms ternary complexes with the chaperonin TCP1 complex, spanning the cylindrical chaperonin cavity and contacting at least 2 subunits.

Similarity:
Contains 1 thioredoxin domain.

SWISS:
O14530

Gene ID:
10190

Database links:

Entrez Gene: 10190 Human

Entrez Gene: 98258 Mouse

Omim: 612564 Human

SwissProt: O14530 Human

SwissProt: Q9CQ79 Mouse

Unigene: 536122 Human

Unigene: 28438 Mouse



产品图片
Sample: HepG2 Cell (Human) Lysate at 40 ug Primary: Anti-TXNDC9 (bs-9429R) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution Predicted band size: 26 kD Observed band size: 28 kD
Tissue/cell: mouse fetal liver; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat s
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