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Rabbit Anti-TSPAN13  antibody (bs-9421R)  
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-9421R
英文名称 Rabbit Anti-TSPAN13  antibody
中文名称 四分子交联体13抗体(四旋蛋白)
别    名 NET 6; NET6; Tetraspan NET-6; Tetraspanin-13; TM4SF13; Transmembrane 4 superfamily member 13; Transmembrane 4 superfamily member tetraspan NET 6; Tspan-13; Tspan13; TSN13_HUMAN.  
研究领域 肿瘤  细胞生物  信号转导  通道蛋白  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 22kDa
细胞定位 细胞核 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPAN13/NET-6: 61-160/204 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).

Similarity:
Belongs to the tetraspanin (TM4SF) family.

SWISS:
O95857

Gene ID:
27075

Database links:

Entrez Gene: 27075 Human

Entrez Gene: 66109 Mouse

Entrez Gene: 366602 Rat

Omim: 613139 Human

SwissProt: Q3ZBV0 Cow

SwissProt: O95857 Human

SwissProt: Q9D8C2 Mouse

SwissProt: Q5FVL6 Rat

Unigene: 49488 Cow

Unigene: 21306 Dog

Unigene: 364544 Human

Unigene: 254663 Mouse

Unigene: 24284 Rat



产品图片
Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TSPAN13) Polyclonal Antibody, Unconjugated (bs-9421R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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