| 产品编号 | bs-9375R |
| 英文名称 | Rabbit Anti-MYCBP2 antibody |
| 中文名称 | MYC结合蛋白2抗体 |
| 别 名 | Pam/highwire/rpm-1 protein; Phr1; MYC binding protein 2; PAM; Pam, highwire, rpm 1; Protein associated with Myc; Probable E3 ubiquitin-protein ligase MYCBP2; Myc-binding protein 2; Pam/highwire/rpm-1 protein; Protein associated with Myc; MYCB2_HUMAN. |
| 研究领域 | 细胞生物 信号转导 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Sheep,Dog,Horse) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 510kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MYCBP2: 21-120/4640 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
MYCBP2 belongs to the highwire family. It is a probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. MYCBP2 may function as a facilitator or regulator of transcriptional activation by MYC and have a role during synaptogenesis. There are two different isoforms. Function: Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis. Subunit: Interacts with MYC. Interacts with TSC2 (tuberin) when TSC2 is in complex with TSC1 (hamartin). Interacts with FBXO45. Subcellular Location: Nuclear Tissue Specificity: Expressed in all tissues examined, expression is exceptionally abundant in brain and thymus. Colocalizes with TSC1 and TSC2 along the neurites and in the growth cones. Colocalized with TSC1 in one of the filopodial extensions at the tip of a growth cone. Similarity: Belongs to the highwire family. Contains 1 B box-type zinc finger. Contains 1 DOC domain. Contains 1 filamin repeat. Contains 5 RCC1 repeats. Contains 1 RING-type zinc finger. SWISS: O75592 Gene ID: 23077 Database links: Entrez Gene: 23077 Human Entrez Gene: 105689 Mouse Omim: 610392 Human SwissProt: O75592 Human SwissProt: Q7TPH6 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
