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MARCH11 Rabbit pAb (bs-9345R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-9345R
英文名称 MARCH11 Rabbit pAb
中文名称 膜相关环指蛋白11抗体
别    名 E3 ubiquitin-protein ligase MARCH11; MARCH-XI; March11; MARHB_HUMAN; Membrane associated ring finger(C3HC4) 11; Membrane-associated RING finger protein 11; Membrane-associated RING-CH protein XI.  
研究领域 细胞生物  免疫学  通道蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Sheep,Cow,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 44 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MARCH11: 301-400/402 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.

Function:
E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids (By similarity).

Subunit:
Interacts (YXXL motif) with AP1M1. Interacts (via PDZ-binding motif) with LIN7A. Interacts with unidentified fucose glycoproteins (By similarity).

Subcellular Location:
Cytoplasmic vesicle membrane; Multi-pass membrane protein (By similarity).

Similarity:
Contains 1 RING-CH-type zinc finger.

SWISS:
A6NNE9

Gene ID:
441061

Database links:

Entrez Gene: 441061 Human

Omim: 613338 Human

SwissProt: A6NNE9 Human

Unigene: 662216 Human



产品图片
Sample: Siha(Human) Cell Lysate at 30 ug Primary: Anti- MARCH11 (bs-9345R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kD Observed band size: 44 kD
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