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AKIRIN2 Rabbit pAb (bs-9082R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-9082R
英文名称 AKIRIN2 Rabbit pAb
中文名称 AKIRIN2蛋白抗体
别    名 AKIR2_HUMAN; AKIRIN 2; Akirin-2; Akirin2; C6orf166; dJ486L4.2; FBI1; FLJ10342; Fourteen three three beta interactant 1.  
研究领域 细胞生物  免疫学  染色质和核信号  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Chicken,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 22 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKIRIN2: 51-150/203 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.

Function:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

Subunit:
Interacts with YWHAB (By similarity).

Subcellular Location:
Nucleus

Tissue Specificity:
Widely expressed with the highest expression in peripheral blood leukocytes

Similarity:
Belongs to the akirin family.

SWISS:
Q53H80

Gene ID:
55122

Database links:

Entrez Gene: 55122 Human

Entrez Gene: 433693 Mouse

Entrez Gene: 297968 Rat

Omim: 615165 Human

SwissProt: Q53H80 Human

SwissProt: B1AXD8 Mouse

SwissProt: Q25C79 Rat

Unigene: 485915 Human

Unigene: 389532 Mouse

Unigene: 399624 Mouse

Unigene: 3858 Rat



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