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PAR3 Rabbit pAb (bs-9510R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-9510R
英文名称 PAR3 Rabbit pAb
中文名称 蛋白酶激活受体3抗体
别    名 Proteinase Activated Receptor 3; coagulation factor II(thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Thrombin receptor-like 2.  
Specific References  (2)     |     bs-9510R has been referenced in 2 publications.
[IF=2.272] Liu et al. Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer. (2016) Onco.Targets.Ther. 9:4121-7  WB ;  Human.  
[IF=1.56] Huang, Chao, et al. "Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis. Corrigendum in/10.3892/mmr. 2016.5882." Molecular Medicine Reports 14.3 (2016): 2555-2565.  IHC-P ;  Human.  
研究领域 心血管  细胞生物  信号转导  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 42 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAR3: 121-220/374 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Tissue specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Function:
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Post-translational modifications:
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
O00254

Gene ID:
2151

Database links:

Entrez Gene: 2151 Human

Omim: 601919 Human

SwissProt: Q58D85 Cow

SwissProt: O00254 Human

Unigene: 24447 Cow

Unigene: 136948 Human

Unigene: 42502 Human



产品图片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- PAR3 (bs-9510R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 57 kD
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