产品编号 | bs-4710R |
英文名称 | SLCO2A1 Rabbit pAb |
中文名称 | 溶质载体蛋白家族21成员2抗体 |
别 名 | MATR1; Matrin F/G 1; OATP2A1; PGT; SO2A1_HUMAN; PHOAR2; Prostaglandin transporter; SLC21A2; Solute carrier family 21(prostaglandin transporter) member 2; Solute carrier family 21 member 2; Solute carrier organic anion transporter family member 2A1. |
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Specific References (1) | bs-4710R has been referenced in 1 publications.
[IF=2.74] Nanase Takahashi. et al. Up-regulation of cytosolic prostaglandin E synthase in fetal-membrane and amniotic prostaglandin E2 accumulation in labor. Plos One. 2021 Apr;16(4):e0250638 IHC ; Human.
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研究领域 | 细胞生物 免疫学 信号转导 通道蛋白 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse (predicted: Human,Rat) |
产品应用 | WB=1:500-2000,Flow-Cyt=3ug/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 70 kDa |
检测分子量 | |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PGT/Slco2a1: 611-643/643 <Cytoplasmic> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
The organic anion transporting polypeptide (OATP) family of proteins play a role in drug absorption, distribution and excretion. OATP proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. PGT, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or OATP2A1, is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, PGT is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding PGT maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Function: May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Ubiquitous. Similarity: Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain. SWISS: Q92959 Gene ID: 6578 Database links: Entrez Gene: 6578 Human Omim: 601460 Human SwissProt: Q92959 Human Unigene: 518270 Human |
产品图片 |
Sample:
Kidney (Mouse) Lysate at 40 ug
Primary: Anti-SLCO2A1 (bs-4710R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kD
Observed band size: 75 kD
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |