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CYBR1 Rabbit pAb (bs-8297R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-8297R
英文名称 CYBR1 Rabbit pAb
中文名称 细胞色素B还原酶1抗体
别    名 CYBR-1; CYBR 1; CYBR1_HUMAN; CYBRD 1; CYBRD1; Cytochrome b reductase 1; DCYTB; DKFZp564E227; Duodenal cytochrome b; Ferric chelate reductase 3; Ferric-chelate reductase 3; FLJ23462; FRRS3.  
Specific References  (1)     |     bs-8297R has been referenced in 1 publications.
[IF=5.008] Rychtarcikova, Zuzana, et al. "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." Oncotarget (2016).  WB ;  Human.  
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 31 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYBR1/Cytochrome b reductase 1: 51-150/286 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

Function:
Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium.

Similarity:
Contains 1 cytochrome b561 domain.

SWISS:
Q53TN4

Gene ID:
79901

Database links:

Entrez Gene: 79901 Human

Entrez Gene: 73649 Mouse

Entrez Gene: 295669 Rat

Omim: 605745 Human

SwissProt: Q53TN4 Human

SwissProt: Q925G2 Mouse

SwissProt: Q5RKJ2 Rat

Unigene: 726027 Human

Unigene: 741213 Human

Unigene: 45435 Mouse

Unigene: 203500 Rat



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