| 产品编号 | bs-8164R |
| 英文名称 | TBL1Y |
| 中文名称 | 转导β样蛋白1抗体 |
| 别 名 | Y-linked; F-box-like/WD repeat-containing protein TBL1Y; TBL1; TBL1Y; TBL1Y_HUMAN; Transducin (beta) like 1, Y linked; Transducin beta-like 1; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Transducin-beta-like protein 1, Y-linked. |
| 研究领域 | 肿瘤 细胞生物 免疫学 染色质和核信号 信号转导 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 57kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TBL1Y: 351-450/522 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. Function: F-box-like protein involved in the recruitment of theubiquitin/19S proteasome complex to nuclear receptor-regulatedtranscription units. Plays an essential role in transcriptionactivation mediated by nuclear receptors. Probably acts as integralcomponent of corepressor complexes that mediates the recruitment ofthe 19S proteasome complex, leading to the subsequent proteasomaldegradation of transcription repressor complexes, thereby allowingcofactor exchange (By similarity). Subunit: Probable component of the N-Cor repressor complex andsome E3 ubiquitin ligase complex (By similarity). Subcellular Location: Nucleus (By similarity). Tissue Specificity: Fetal brain and prostate. Similarity: Belongs to the WD repeat EBI family. Contains 1 F-box-like domain. Contains 1 LisH domain. Contains 8 WD repeats. SWISS: Q9BQ87 Gene ID: 90665 Database links:
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
