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Rabbit Anti-AGFG1  antibody (bs-8072R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-8072R
英文名称 AGFG1
中文名称 艾滋病病毒复制结合蛋白抗体
别    名 HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.  
研究领域 细胞生物  免疫学  信号转导  细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Horse)
产品应用 WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58kDa
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AGFG1: 276-380/562 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication.

Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.

Subcellular Location:
Nucleus. Cytoplasmic vesicle.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
O-glycosylated (By similarity).

Similarity:
Contains 1 Arf-GAP domain.

SWISS:
P52594

Gene ID:
3267

Database links:

Entrez Gene: 536149 Cow

Entrez Gene: 3267 Human

Entrez Gene: 15463 Mouse

Entrez Gene: 363266 Rat

Omim: 600862 Human

SwissProt: Q2TA45 Cow

SwissProt: P52594 Human

SwissProt: Q8K2K6 Mouse

SwissProt: Q4KLH5 Rat

Unigene: 352962 Human

Unigene: 392569 Mouse

Unigene: 433409 Mouse

Unigene: 3734 Rat



产品图片
Sample:
Heart (Mouse) Lysate at 40 ug
Primary: Anti- AGFG1 (bs-8072R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58kD
Observed band size: 55 kD
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