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Rabbit Anti-PELO  antibody (bs-7821R)  
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-7821R
英文名称 Rabbit Anti-PELO  antibody
中文名称 PELO蛋白抗体
别    名 CGI17; pelo; PELO_HUMAN; pelota (Drosophila) homolog; pelota homolog; PRO1770; Protein pelota homolog.  
Specific References  (2)     |     bs-7821R has been referenced in 2 publications.
[IF=5.636] Nele Hug. et al. A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation. RNA. 2022 Sep;28(9):1224-1238  IP, WB ;  Human.  
[IF=3.231] Peifang Yang. et al. A Proteomic Study of the Effect of N-acetylcysteine on the Regulation of Early Pregnancy in Goats. ANIMALS. 2022 Jan;12(18):2439  IHC ;  Goat.  
研究领域 细胞生物  细胞周期蛋白  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Cow,Chicken,Dog,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 43kDa
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PELO: 141-240/385 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.

Function:
Required for normal chromosome segregation during celldivision and genomic stability (By similarity). May function inrecognizing stalled ribosomes and triggering endonucleolyticcleavage of the mRNA, a mechanism to release non-functionalribosomes and degrade damaged mRNAs. May have ribonuclease activity(Potential).

Subcellular Location:
Nucleus (Potential). Cytoplasm (Bysimilarity).

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the eukaryotic release factor 1 family.Pelota subfamily.

SWISS:
Q9BRX2

Gene ID:
53918

Database links:

Entrez Gene: 53918 Human

Omim: 605757 Human

SwissProt: Q9BRX2 Human

Unigene: 644352 Human

Unigene: 669791 Human



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