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Rabbit Anti-MAL  antibody (bs-4693R)  
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-4693R
英文名称 Rabbit Anti-MAL  antibody
中文名称 MAL蛋白抗体
别    名 mal; MAL protein gene; Mal T-cell differentiation protein; MAL_HUMAN; MALGENE; MPV17; Myelin and lymphocyte protein; T-cell differentiation protein MAL; T-lymphocyte maturation-associated protein; VIP17.  
研究领域 细胞生物  免疫学  神经生物学  细胞凋亡  细胞周期蛋白  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 17kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAL: 65-153/153 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, Jul 2008].

Function:
Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Post-translational modifications:
Lipoprotein.

Similarity:
Belongs to the MAL family.
Contains 1 MARVEL domain.

SWISS:
P21145

Gene ID:
4118

Database links:

Entrez Gene: 4118 Human

Entrez Gene: 17153 Mouse

Entrez Gene: 25263 Rat

Omim: 188860 Human

SwissProt: Q28296 Dog

SwissProt: P21145 Human

SwissProt: O09198 Mouse

SwissProt: Q64349 Rat

Unigene: 80395 Human

Unigene: 39040 Mouse

Unigene: 10174 Rat



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