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Rabbit Anti-CLUAP1  antibody (bs-6805R)  
~~~促销代码KT202411~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-6805R
英文名称 Rabbit Anti-CLUAP1  antibody
中文名称 成簇相关蛋白1抗体
别    名 Clusterin associated protein 1; FLJ13297; KIAA0643; CLUA1_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Chicken,Dog,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 48kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLUAP1: 35-140/413 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Function:
May play a role in cell proliferation or apoptosis.

Subunit:
Interacts with CLU/clusterin.

Subcellular Location:
Nuclear

Tissue Specificity:
Expressed in testis, thyroid and trachea and to a lower extent in spinal cord and adrenal gland.

SWISS:
Q96AJ1

Gene ID:
23059

Database links:

Entrez Gene: 23059 Human

Entrez Gene: 76779 Mouse

Entrez Gene: 363544 Rat

SwissProt: Q96AJ1 Human

SwissProt: Q8R3P7 Mouse

SwissProt: Q6AYJ5 Rat

Unigene: 155995 Human

Unigene: 458921 Mouse

Unigene: 19522 Rat



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