产品编号 | bs-6805R |
英文名称 | Rabbit Anti-CLUAP1 antibody |
中文名称 | 成簇相关蛋白1抗体 |
别 名 | Clusterin associated protein 1; FLJ13297; KIAA0643; CLUA1_HUMAN. |
研究领域 | 肿瘤 细胞生物 免疫学 肿瘤细胞生物标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Chicken,Dog,Horse) |
产品应用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 48kDa |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CLUAP1: 35-140/413 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: May play a role in cell proliferation or apoptosis. Subunit: Interacts with CLU/clusterin. Subcellular Location: Nuclear Tissue Specificity: Expressed in testis, thyroid and trachea and to a lower extent in spinal cord and adrenal gland. SWISS: Q96AJ1 Gene ID: 23059 Database links: Entrez Gene: 23059 Human Entrez Gene: 76779 Mouse SwissProt: Q96AJ1 Human SwissProt: Q8R3P7 Mouse Unigene: 155995 Human Unigene: 458921 Mouse Unigene: 19522 Rat |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |