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THRSP Rabbit pAb (bs-6738R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-6738R
英文名称 THRSP Rabbit pAb
中文名称 甲状腺激素反应蛋白抗体
别    名 Lpgp; LPGP1; S14; S14 protein; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein; Thyroid hormone responsive(SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein;  
研究领域 肿瘤  细胞生物  信号转导  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Rabbit)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 17 kDa
检测分子量
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human THRSP: 116-145/146 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.Mainly expressed in tissues that synthesize triglycerides.

Function:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

Subunit:
Homodimer. Heterodimer with MID1IP1. Interacts with THRB and PLAGL1.

Subcellular Location:
Cytoplasm.Nucleus.

Tissue Specificity:
Mainly expressed in tissues that synthesize triglycerides.

Similarity:
Mainly expressed in tissues that synthesize triglycerides.
Belongs to the SPOT14 family.

SWISS:
Q92748

Gene ID:
7069

Database links:

Entrez Gene: 7069 Human

Entrez Gene: 21835 Mouse

Entrez Gene: 25357 Rat

Omim: 601926 Human

SwissProt: Q92748 Human

SwissProt: Q62264 Mouse

SwissProt: P04143 Rat

Unigene: 591969 Human

Unigene: 28585 Mouse

Unigene: 81140 Rat



产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (THRSP) Polyclonal Antibody, Unconjugated (bs-6738R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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