| 产品编号 | bs-6543R |
| 英文名称 | LDOC1 |
| 中文名称 | 癌症亮氨酸拉链下调因子1抗体 |
| 别 名 | BCUR1; Breast cancer up regulated 1; Breast cancer upregulated 1; Gm366; Leucine zipper down regulated in cancer 1; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down regulated in cancer cells; Mar7; Mart7; Protein LDOC1; RGD1565644; LDOC1_HUMAN . |
| 研究领域 | 肿瘤 染色质和核信号 信号转导 转录调节因子 肿瘤细胞生物标志物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Dog,Pig,Horse,Rabbit) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 17kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LDOC1: 65-146/146 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008].
Function: May have an important role in the development and/or progression of some cancers. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously expressed with high levels in brain and thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined. Similarity: Belongs to the LDOC1 family. SWISS: O95751 Gene ID: 23641 Database links: Entrez Gene: 23641 Human Omim: 300402 Human SwissProt: O95751 Human Unigene: 45231 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
