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Rabbit Anti-RAB2  antibody (bs-6174R)  
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-6174R
英文名称 Rabbit Anti-RAB2  antibody
中文名称 ras癌基因家族Rab2抗体
别    名 GTP binding protein; RAB2; RAB2 member RAS oncogene family; RAB2A; RAB2A, member RAS oncogene family; RAB2A_HUMAN; Ras related protein Rab 2A; RAS-associated protein RAB2; Ras-related protein Rab-2A; RP23-183L6.1  
研究领域 肿瘤  细胞生物  信号转导  转录调节因子  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 23kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAB2: 101-200/212 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Function:
Required for protein transport from the endoplasmic reticulum to the Golgi complex.

Subunit:
Interacts with PRKCI.

Subcellular Location:
Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor (Potential). Golgi apparatus membrane; Lipid-anchor (Potential). Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
P61019

Gene ID:
5862

Database links:

Entrez Gene: 5862 Human

Entrez Gene: 59021 Mouse

Entrez Gene: 65158 Rat

Omim: 179509 Human

SwissProt: P61019 Human

SwissProt: P53994 Mouse

SwissProt: P05712 Rat

Unigene: 369017 Human

Unigene: 397471 Mouse

Unigene: 467703 Mouse

Unigene: 44916 Rat



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