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Rabbit Anti-VILIP1  antibody (bs-6118R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-6118R
英文名称 Rabbit Anti-VILIP1  antibody
中文名称 神经视锥蛋白样1(神经钙蛋白)抗体
别    名 VISL1_HUMAN; Visinin-like protein 1; Visinin like protein 1; Hippocalcin-like protein 3; visinin-like protein 1 isoform 3; Neurocalcin alpha; HLP3; HLP 3; HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1; VLP-1; VISL 1; VSNL1.  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  结合蛋白  Alzheimer's  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Pig,Cow,Chicken)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 22kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VILIP1: 121-191/191 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Function:
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

Tissue Specificity:
Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).

Similarity:
Belongs to the recoverin family.
Contains 4 EF-hand domains.

SWISS:
P62760

Gene ID:
7447

Database links:

Entrez Gene: 396189 Chicken

Entrez Gene: 282124 Cow

Entrez Gene: 7447 Human

Entrez Gene: 26950 Mouse

Entrez Gene: 24877 Rat

Omim: 600817 Human

SwissProt: P62764 Chicken

SwissProt: P62763 Cow

SwissProt: P62760 Human

SwissProt: P62761 Mouse

SwissProt: P62762 Rat

Unigene: 444212 Human

Unigene: 27005 Mouse

Unigene: 105934 Rat



产品图片
Sample: Recombinant human VILIP1 protein at 100 ng Primary: Anti-VILIP1 (bs-6118R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 20 kD
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