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CDH6 Rabbit pAb (bs-5823R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-5823R
英文名称 CDH6 Rabbit pAb
中文名称 钙粘蛋白6抗体
别    名 CADH6_HUMAN; Cadherin-6; Kidney cadherin (K-cadherin); CAD6; KCAD;  
研究领域 肿瘤  细胞生物  免疫学  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human (predicted: Mouse,Rat,Cow,Horse)
产品应用 Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 82 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human K Cadherin: 281-380/790 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 K Cadherin (Cadherin 6) is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells. K Cadherin is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. It is also expressed in certain liver and kidney carcinomas.

Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.

Similarity:
Contains 5 cadherin domains.

SWISS:
P55285

Gene ID:
1004

Database links:

Entrez Gene: 1004 Human

Entrez Gene: 12563 Mouse

Entrez Gene: 25409 Rat

Omim: 603007 Human

SwissProt: P55285 Human

SwissProt: P97326 Mouse

SwissProt: P55280 Rat

Unigene: 124776 Human

Unigene: 171054 Human

Unigene: 57048 Mouse

Unigene: 10390 Rat



产品图片
Histogram of MCF-7 cells stained with anti-K-cadherin (orange), isotype control antibody (green), secondary antibody only (blue) and unstained (red).
Histogram of 786-O cells stained with anti-K-cadherin (orange), isotype control antibody (green), secondary antibody only (blue) and unstained (red).
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