| 产品编号 | bs-5790R |
| 英文名称 | LOXL4 Rabbit pAb |
| 中文名称 | 赖氨酰氧化酶样蛋白4抗体 |
| 别 名 | LOXC; 4833426I20Rik; LOXL4_HUMAN; LOXL4; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C; 1.4.3.13; LOXL4_MOUSE; |
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Specific References (1) | bs-5790R has been referenced in 1 publications.
[IF=2.037] Kasashima H et al. Significance of the Lysyl Oxidase Members Lysyl Oxidase Like 1, 3, and 4 in Gastric Cancer.Digestion. 2018;98(4):238-248. IHC-P&WB ; Human.
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| 研究领域 | 肿瘤 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 82 kDa |
| 细胞定位 | 细胞外基质 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LOXL4: 101-200/756 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Function: May modulate the formation of a collagenous extracellular matrix. Subcellular Location: Secreted, extracellular space Tissue Specificity: Expressed in many tissues, the highest levels among the tissues studied being in the skeletal muscle, testis and pancreas. Expressed in cartilage. Post-translational modifications: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine. Similarity: Belongs to the lysyl oxidase family. Contains 4 SRCR domains. SWISS: Q96JB6 Gene ID: 84171 Database links: Entrez Gene: 84171 Human Entrez Gene: 67573 Mouse Omim: 607318 Human SwissProt: Q96JB6 Human SwissProt: Q924C6 Mouse Unigene: 306814 Human Unigene: 671890 Human Unigene: 178767 Mouse |
| 产品图片 |
Sample:
A549(Human) Cell Lysate at 30 ug
Primary: Anti-LOXL4 (bs-5790R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 82 kD
Observed band size: 82 kD
Sample:
293T(Human) Cell Lysate at 30 ug
Primary: Anti-LOXL4 (bs-5790R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 82 kD
Observed band size: 82 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
