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GPR39 Rabbit pAb (bs-5789R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-5789R
英文名称 GPR39 Rabbit pAb
中文名称 G蛋白偶联受体39抗体
别    名 GPCR GPR39; G protein coupled receptor GPR39; G Protein-Coupled Receptor 39; G-protein coupled receptor 39; GPR 39; GPR39; GPR-39; MGC149541.  
研究领域 细胞生物  免疫学  信号转导  细胞膜受体  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,Rat (predicted: Human,Rabbit,Cow,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 51 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR39.: 251-350/453 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 GPCR39 is an integral membrane protein, which belongs to family 1 of G-protein coupled receptors. GPCR39 expression has been documented in human brain and peripheral tissues. ESTs have been isolated from human tissue libraries, including normal eye, brain, heart, melanocyte, uterus, vessel, cancerous brain, germ cell, kidney, and ovary.

Function:
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.

Subcellular Location:
Multi-pass membrane protein

Tissue Specificity:
Expressed in many tissues, including the stomach, intestine and hypothalamus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
O43194

Gene ID:
2863

Database links:

Entrez Gene: 2863 Human

Entrez Gene: 71111 Mouse

Entrez Gene: 288995 Rat

Omim: 602886 Human

SwissProt: O43194 Human

SwissProt: Q5U431 Mouse



产品图片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; A
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Anti
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