| 产品编号 | bs-1264R |
| 英文名称 | RSV G Rabbit pAb |
| 中文名称 | 呼吸道合胞病毒G抗体 |
| 别 名 | RS virus; RSV; GLYC_HRSVA; Major surface glycoprotein G; Attachment glycoprotein G; Membrane-bound glycoprotein; mG; G. 呼吸道合胞病毒主要表面糖蛋白G; |
 |
Specific References (6) | bs-1264R has been referenced in 6 publications.
[IF=20.693] Yu Mao. et al. Lung-brain axis: Metabolomics and Pathological changes in lungs and brain of Respiratory syncytial virus infected mice. J MED VIROL. 2022 Aug;: IF ; Mouse.
[IF=20.693] Pei Dai. et al. Gimap5 promoted RSV degradation through interaction with M6PR. J MED VIROL. 2022 Dec;: IF ; Mouse, Human.
[IF=6.377] Pei Dai. et al. The dispersion and utilization of lipid droplets mediates respiratory syncytial virus-induced airway hyperresponsiveness. 2021 Aug 12 IF ; Mouse.
[IF=5.758] Dai Pei. et al. The antiviral efficacies of small-molecule inhibitors against respiratory syncytial virus based on the F protein. J ANTIMICROB CHEMOTH. 2022 Nov;: IF ; Human.
[IF=5.168] Dan Liu. et al. miR-34b/c-5p/CXCL10 Axis Induced by RSV Infection Mediates a Mechanism of Airway Hyperresponsive Diseases. BIOLOGY-BASEL. 2023 Feb;12(2):317 IF ; Mouse.
[IF=3.411] Liu Dan. et al. RSV Promotes Epithelial Neuroendocrine Phenotype Differentiation through NODAL Signaling Pathway. Biomed Res Int. 2021;2021:9956078 IF ; human.
|
| 研究领域 | 细胞生物 免疫学 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | HRSVA |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 33 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 细胞外基质 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human respiratory syncytial virus A2: 151-250/298 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. Function: Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors. Subunit: Homooligomer. Interacts (via N-terminus) with protein M. Interacts with protein F; this interaction occurs on the surface of infected cells. Interacts with protein SH. Interacts with host CX3CR1; this interaction modulates host immune response. Subcellular Location: Virion membrane. Host cell surface. Isoform Secreted glycoprotein G: Secreted. Post-translational modifications: May carry 40-80 separate O-linked carbohydrate chains distributed among the 91 serine and threonine residues. Palmitoylated. Similarity: Belongs to the pneumoviruses glycoprotein G family. Gene ID: RSV Database links:
呼吸道合胞病毒引起的急性呼吸道传染病，该病毒能使病变细胞融合成多核巨细胞，故称此名。 呼吸道合胞病毒是一种RNA病毒，属副粘液病毒科。该病经空气飞沫和密切接触传播。多见于新生儿和6 个月以内的婴儿。潜伏期3～7日。婴幼儿症状较重，可有高热、鼻炎、咽炎及喉炎，以后表现为细支气管炎及肺炎。少数病儿可并发中耳炎、胸膜炎及心肌炎等。成人和年长儿童感染后，主要表现为上呼吸道感染。 |
| 产品图片 |
Sample:
Lane 1: Recombinant HRSVA Major surface glycoprotein G protein (HEK293)(bs-43661P)
Primary: Anti-RSV G (bs-1264R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kDa
Observed band size: 90
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
