| 产品编号 | bs-4180R |
| 英文名称 | Rabbit Anti-P2Y2 antibody |
| 中文名称 | 嘌呤ATP受体抗体 |
| 别 名 | P2Y2R; ATP receptor; HP2U; Human P2U nucleotide receptor mRNA complete cds; P2RU1; P2RY2; P2RY2_HUMAN; P2U nucleotide receptor; P2U purinoceptor 1; P2U1; P2UR; P2Y purinoceptor 2; P2Y2; P2Y2R; Purinergic receptor; Purinergic receptor P2Y G protein coupled 2; Purinergic receptor P2Y2; Purinoceptor P2Y2. |
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Specific References (3) | bs-4180R has been referenced in 3 publications.
[IF=4.162] Zhen-Ni Liu. et al. Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway. DRUG DES DEV THER. Drug Des Dev Ther. 2022 Apr;16:1107-1120 IHC ; Mouse.
[IF=3.361] Liu ZN et al. Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation. Int Immunopharmacol. 2019 Oct 19;77:105915. WB ; Mouse.
[IF=1.42] Liu, Yuan-Mei, et al. "Expression of the P2Y2 receptor in the terminal rectum of fetal rats with anorectal malformation." International Journal of Clinical and Experimental Medicine 8.2 (2015): 1669-1676. IHC-P ; Rat.
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| 研究领域 | 免疫学 转录调节因子 G蛋白偶联受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Dog,Horse) |
| 产品应用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 41kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P2Y2R: 21-120/377 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]. Function: Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Spleen, testis, kidney, liver, lung, heart and brain. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P41231 Gene ID: 5029 Database links: Entrez Gene: 5029 Human Entrez Gene: 18442 Mouse Omim: 600041 Human SwissProt: P41231 Human SwissProt: P35383 Mouse Unigene: 339 Human Unigene: 3000 Mouse Unigene: 11102 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
