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Rabbit Anti-P2Y2  antibody (bs-4180R)  
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-4180R
英文名称 Rabbit Anti-P2Y2  antibody
中文名称 嘌呤ATP受体抗体
别    名 P2Y2R; ATP receptor; HP2U; Human P2U nucleotide receptor mRNA complete cds; P2RU1; P2RY2; P2RY2_HUMAN; P2U nucleotide receptor; P2U purinoceptor 1; P2U1; P2UR; P2Y purinoceptor 2; P2Y2; P2Y2R; Purinergic receptor; Purinergic receptor P2Y G protein coupled 2; Purinergic receptor P2Y2; Purinoceptor P2Y2.  
Specific References  (3)     |     bs-4180R has been referenced in 3 publications.
[IF=4.162] Zhen-Ni Liu. et al. Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway. DRUG DES DEV THER. Drug Des Dev Ther. 2022 Apr;16:1107-1120  IHC ;  Mouse.  
[IF=3.361] Liu ZN et al. Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation. Int Immunopharmacol. 2019 Oct 19;77:105915.  WB ;  Mouse.  
[IF=1.42] Liu, Yuan-Mei, et al. "Expression of the P2Y2 receptor in the terminal rectum of fetal rats with anorectal malformation." International Journal of Clinical and Experimental Medicine 8.2 (2015): 1669-1676.  IHC-P ;  Rat.  
研究领域 免疫学  转录调节因子  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Rabbit,Dog,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 41kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2Y2R: 21-120/377 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].

Function:
Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Spleen, testis, kidney, liver, lung, heart and brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P41231

Gene ID:
5029

Database links:

Entrez Gene: 5029 Human

Entrez Gene: 18442 Mouse

Entrez Gene: 29597 Rat

Omim: 600041 Human

SwissProt: P41231 Human

SwissProt: P35383 Mouse

SwissProt: P41232 Rat

Unigene: 339 Human

Unigene: 3000 Mouse

Unigene: 11102 Rat



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