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Rabbit Anti-phospho-KCNC1 (Ser503)  antibody (bs-5403R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-5403R
英文名称 Rabbit Anti-phospho-KCNC1 (Ser503)  antibody
中文名称 磷酸化离子通道蛋白Kv3.1抗体
别    名 KCNC1 (phospho S503); p-KCNC1 (phospho Ser503); C230009H10Rik; FLJ41162; FLJ42249; FLJ43491; Kcr2 1; KShIIIB; Kv3.1; Kv4; MGC129855; NGK2; Potassium voltage-gated channel subfamily C member 1; Shaw; Voltage gated potassium channel; KCNC1_RAT; Voltage gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv3.1; KCNC1_RAT.  
Specific References  (1)     |     bs-5403R has been referenced in 1 publications.
[IF=4.636] Cheng Wanpeng. et al. Transcriptomic analysis reveals the effects of maternal selenium deficiency on placental transport, hormone synthesis, and immune response in mice. METALLOMICS. 2022 Aug;:  WB ;  Mouse.  
产品类型 磷酸化抗体 
研究领域 细胞生物  免疫学  神经生物学  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Chicken,Dog,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from rat KCNC1 around the phosphorylation site of Ser503: AD(p-S)KL 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.

Function:
This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Subunit:
Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.

SWISS:
P25122

Gene ID:
25327

Database links:

Entrez Gene: 3746 Human

Entrez Gene: 16502 Mouse

Entrez Gene: 25327 Rat

Omim: 176258 Human

SwissProt: P48547 Human

SwissProt: P15388 Mouse

SwissProt: P25122 Rat

Unigene: 303870 Human

Unigene: 552896 Human

Unigene: 249386 Mouse

Unigene: 33095 Rat



产品图片
Sample: Lane 1: Mouse Cerebellum tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kDa Observed band size: 53 kDa
Sample: Hela(Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
Sample: HL60(Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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