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产品中心-北京博奥森生物技术有限公司
Bcl-2 Antibody Blocking Peptide (bs-0032P)  
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500ug/880.00元
大包装/询价
产品编号 bs-0032P
英文名称 Bcl-2 Antibody Blocking Peptide
中文名称 Bcl-2封闭多肽
别    名 Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-ce  
Specific References  (1)     |     bs-0032P has been referenced in 1 publications.
[IF=0.754] Su XY et al. Chemoprotective Effects of Resveratrol Against Diethylnitrosamine Induced Hepatocellular Carcinoma in Wistar Rats. Int. J. Pharmacol.,2019 15 (5): 549-559.  Other ;  
理论分子量 kDa
检测分子量
性    状 Lyophilized
物    种 human
纯化方法 HPLC
活性 Not tested
保存条件 Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
产品介绍 The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8).

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