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OXCT1 Rabbit pAb (bs-5089R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-5089R
英文名称 OXCT1 Rabbit pAb
中文名称 含氧酸辅酶A转移酶1抗体
别    名 mitochondrial; 3 oxoacid CoA transferase 1; 3-oxoacid-CoA transferase 1; OXCT; Oxct1; SCOT; Scot S; Scot-S; SCOT1_HUMAN; Somatic type succinyl CoA:3 oxoacid CoA transferase; Somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; Succinyl CoA:3 ketoacid CoA   
研究领域 肿瘤  细胞生物  转录调节因子  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 56 kDa
检测分子量
细胞定位 细胞浆 线粒体
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OXCT1: 211-310/520 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Function:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.

DISEASE:
Defects in OXCT1 are a cause of SCOT deficiency (SCOTD) [MIM:245050].

Similarity:
Belongs to the 3-oxoacid CoA-transferase family.

SWISS:
P55809

Gene ID:
5019

Database links:

Entrez Gene: 5019 Human

Entrez Gene: 67041 Mouse

Entrez Gene: 690163 Rat

Omim: 601424 Human

SwissProt: P55809 Human

SwissProt: Q9D0K2 Mouse

SwissProt: B2GV06 Rat

Unigene: 278277 Human

Unigene: 13445 Mouse

Unigene: 98472 Rat



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