| 产品编号 | bs-2394R |
| 英文名称 | Rabbit Anti-CKLF antibody |
| 中文名称 | 趋化素样蛋白抗体 |
| 别 名 | C32; Chemokine-like factor; chemokine-like factor 1; chemokine-like factor 2; chemokine-like factor 3; chemokine-like factor 4; CKLF_HUMAN; CKLF1; CKLF2; CKLF3; CKLF4; CKLFSF2; HSPC224; transmembrane proteolipid; UCK-1; UCK1. |
| 研究领域 | 肿瘤 细胞生物 免疫学 细胞分化 淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse,Rat (predicted: Rabbit) |
| 产品应用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 17kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CKLF: 1-100/152 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011] Function: May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10. Isoform 1 has chemotactic response in rat monocytes, neutrophils, and lymphocytes. Subcellular Location: Isoform 1: Secreted. Isoform 2: Membrane; Multi-pass membrane protein. Isoform 4: Membrane; Multi-pass membrane protein. Tissue Specificity: Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver. Similarity: Belongs to the chemokine-like factor family. Contains 1 MARVEL domain. SWISS: Q9UBR5 Gene ID: 51192 Database links: Entrez Gene: 51192 Human Entrez Gene: 75458 Mouse Omim: 607885 Human SwissProt: Q9UBR5 Human SwissProt: Q9DAS1 Mouse Unigene: 15159 Human Unigene: 81197 Rat CKLF（趋化素样因子）是人类趋化素样因子超家族CKLFSF（Chemokine-like Factor Super Family，趋化素样因子超家族）中的一员，趋化因子能使细胞发生趋化运动的小分子细胞因子。趋化因子结构和功能比较相似,分子量多在10-20kDa之间,对嗜中性粒细胞、淋巴细胞、单核细胞等多种细胞有趋化活性。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
