| 产品编号 | bs-4040R |
| 英文名称 | Rabbit Anti-IL18BP antibody |
| 中文名称 | 白细胞介素18结合蛋白抗体 |
| 别 名 | IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Tadekinig alfa; I18BP_HUMAN; IL-18BP; Interleukin-18-binding protein |
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Specific References (2) | bs-4040R has been referenced in 2 publications.
[IF=5.41] Businaro, Rita, et al. "Interleukin-18 modulation in autism spectrum disorders." Journal of Neuroinflammation 13.1 (2016): 2. WB ; Mouse.
[IF=5.102] Serafino Ricci 2016-01-05. (2016) J.Neuroinflammation. http://www.jneuroinflammation.com/content/13/1/2 WB ; Mouse.
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| 研究领域 | 肿瘤 细胞生物 免疫学 转录调节因子 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse,Rat (predicted: Human,Pig,Cow) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 18kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL18BP: 91-194/194 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
IL18 binding protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18 induced IFN gamma production. It is constitutively expressed and secreted in mononuclear cells and can be enhanced by IFN gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn disease. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. Function: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. Subcellular Location: Secreted. Tissue Specificity: Strongly expressed in heart, lung, placenta and spleen. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. SWISS: O95998 Gene ID: 10068 Database links: Entrez Gene: 10068 Human Omim: 604113 Human SwissProt: O95998 Human Unigene: 591967 Human Unigene: 20083 Rat |
| 产品图片 |
Sample:
Lane 1: Mouse Lymph node tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Mouse Large intestine tissue lysates
Lane 4: Rat Lymph node tissue lysates
Lane 5: Rat Lung tissue lysates
Lane 6: Rat Placenta tissue lysates
Lane 7: Rat Large intestine tissue lysates
Primary: Anti-IL18BP (bs-4040R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 18 kDa
Observed band size: 52 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
