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ADCY4 Rabbit pAb (bs-3921R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-3921R
英文名称 ADCY4 Rabbit pAb
中文名称 腺苷酸环化酶4抗体
别    名 AC4; Adenylate cyclase 4; adenylate cyclase type 4; Adenylate cyclase type IV; Adenylyl cyclase; ATP pyrophosphate lyase 4; ATP pyrophosphate lyase; ADCY4_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  信号转导  生长因子和激素  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 120 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADCY4: 851-1077/1077 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.

Function:
This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

SWISS:
Q8NFM4

Gene ID:
196883

Database links:
UniProtKB/Swiss-Prot: Q8NFM4.1

产品图片
25 ug total protein per lane of various lysates (see on figure) probed with ADCY4 polyclonal antibody, unconjugated (bs-3921R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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