产品编号 | bs-3895R |
英文名称 | SOD3 Rabbit pAb |
中文名称 | 超氧化物歧化酶3抗体 |
别 名 | EC-SOD; Superoxide Dismutase 3; ALS; ALS1; Cu/Zn superoxide dismutase; EC SOD; Extracellular superoxide dismutase [Cu Zn]; Extracellular superoxide dismutase; Extracellular superoxide dismutase precursor; Homodimer; Indophenoloxidase A; IPOA; Mn superoxide dismutase; SOD 3; SOD; SOD soluble; SOD2; SOD3; Superoxide dismutase 3 extracellular; Superoxide dismutase cystolic; SODE_HUMAN; extracellular superoxide dismutase isoform 1. |
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Specific References (4) | bs-3895R has been referenced in 4 publications.
[IF=5.81] Xinyue Chang. et al. The Protective Effect of Trichilia catigua A. Juss. on DEHP-Induced Reproductive System Damage in Male Mice. Front Pharmacol. 2022; 13: 832789 IHC ; Mouse.
[IF=5.195] Xin Zhao. et al. Diammonium glycyrrhizinate ameliorates portal hypertension by regulating portal macrophage oxidation and superoxide dismutase 3. EUR J PHARMACOL. 2022 Jun;:175115 IHC ; Rat.
[IF=3.221] Kobayashi T et al. The characteristic regulation of gene expression Lbp and Sod3 in peri‐implant connective tissue of rats. J Biomed Mater Res A. 2019 Nov 12. IHC-P ; Rat.
[IF=0] SUKADANA IM et al. The Intake of Inocarpus Fagiferus Fosb Stem Bark N-Buthanol Extract Caused the Increase Expression of Sod-2 and Sod-3 Aortic Endhotelial Cells of Hypercholesterolemia Rats. Biomedical and Pharmacology Journal.2017, 10(4):1773-1777 · WB ; Rat.
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研究领域 | 肿瘤 细胞生物 免疫学 染色质和核信号 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
克 隆 号 | |
交叉反应 | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 24 kDa |
检测分子量 | |
细胞定位 | 细胞外基质 分泌型蛋白 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SOD3: 227-240/240 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008] Function: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Subunit: Homotetramer. Subcellular Location: Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. Tissue Specificity: Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. Similarity: Belongs to the Cu-Zn superoxide dismutase family. SWISS: P08294 Gene ID: 6649 Database links: Entrez Gene: 6649 Human Entrez Gene: 20657 Mouse Omim: 185490 Human SwissProt: P08294 Human SwissProt: O09164 Mouse Unigene: 2420 Human Unigene: 2407 Mouse Unigene: 10358 Rat |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |