| 产品编号 | bs-3850R |
| 英文名称 | Rabbit Anti-BCMA antibody |
| 中文名称 | B淋巴细胞成熟因子（CD269）抗体 |
| 别 名 | B cell maturation antigen; B Cell Maturation Factor; B cell maturation protein; BCM; TNFRSF17; CD269; CD269 antigen; Tumor Necrosis Factor Receptor Member 17; Tumor necrosis factor receptor superfamily member 17; TNR17_HUMAN. |
| 研究领域 | 肿瘤 细胞生物 免疫学 转录调节因子 b-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse,Rat |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 20 kDa |
| 检测分子量 | 27 |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BCMA: 12-110/184 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq] Function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. Subunit: Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. Subcellular Location: Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Tissue Specificity: Expressed in mature B-cells, but not in T-cells or monocytes. DISEASE: Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2. Similarity: Contains 1 TNFR-Cys repeat. SWISS: Q02223 Gene ID: 608 Database links: Entrez Gene: 608 Human Omim: 109545 Human SwissProt: Q02223 Human Unigene: 2556 Human |
| 产品图片 |
Sample:
Lane 1: Spleen (Mouse) Lysate at 40 ug
Lane 2: Lymph node (Mouse) Lysate at 40 ug
Lane 3: Spleen (Rat) Lysate at 40 ug
Primary:
Anti-BCMA (bs-3850R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25 kD
Observed band size: 27 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
