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Rabbit Anti-SH2D2A  antibody (bs-3858R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-3858R
英文名称 SH2D2A
中文名称 血管内皮生长因子受体相关蛋白抗体
别    名 SH2D2A/VEGF receptor associated protein SCAP; SH2 domain containing adapter protein; SH2 domain containing protein 2A; SH2 domain protein 2A; T cell specific adapter protein; T cell specific adapter protein TSAd; T cell specific adpater protein TSAd; T lymphocyte specific adaptor protein; TSAd; VEGF receptor associated protein; VRAP.   
Specific References  (1)     |     bs-3858R has been referenced in 1 publications.
[IF=12.35] Compeer et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. (2018) Nat.Commun. 9:1597  IF ;  Mouse.  
研究领域 肿瘤  免疫学  生长因子和激素  血管内皮细胞  t-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,Mouse (predicted: Rat,Dog,Pig,Cow,Horse,Rabbit)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, Flow-Cyt=1μg /Test, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 43kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH2D2A: 101-200/389 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 SH2D2A is thought to be a T-cell-specific adapter protein involved in the control of T-cell activation. It may play a role in the CD4-p56-LCK-dependent signal transduction pathway and also in normal and pathological angiogenesis.

Subunit:
Interacts with KDR. Interacts with TXK and ITK.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
SH2D2A is thought to be a T-cell-specific adapter protein involved in the control of T-cell activation. It may play a role in the CD4-p56-LCK-dependent signal transduction pathway and also in normal and pathological angiogenesis.

Similarity:
Contains 1 SH2 domain.

SWISS:
Q9NP31

Gene ID:
9047

Database links:

Entrez Gene: 9047 Human

Entrez Gene: 27371 Mouse

Omim: 604514 Human

SwissProt: Q9NP31 Human

SwissProt: Q9QXK9 Mouse

Unigene: 103527 Human

Unigene: 86361 Mouse



产品图片
Blank control(blue): HUVEC cells(fixed with 2% paraformaldehyde (10 min),then permeabilized with 90% ice-cold methanol for 30 min on ice).
Primary Antibody:Rabbit Anti- SH2D2A antibody(bs-3858R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions );
Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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