| 产品编号 | bs-3803R |
| 英文名称 | Mammaglobin B Rabbit pAb |
| 中文名称 | 乳腺珠蛋白2抗体 |
| 别 名 | Lipophilin C; LPHC; Mammaglobin 2; MGB2; MGC71973; SCGB2A1; Secretoglobin, family 2A, member 1; UGB3. |
| 研究领域 | 肿瘤 免疫学 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human,Rat,Horse) |
| 产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 8.5 kDa |
| 检测分子量 | |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Mammaglobin B: 41-95/95 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Mammaglobin B may bind androgens and other steroids, it may also bind estramustine, a chemotherapeutic agent used for prostate cancer. It may be under transcriptional regulation of steroid hormones. Subunit: Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head. Tissue Specificity: Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. Gene ID: 4246 乳腺球蛋白是一个乳腺相关糖蛋白，它是一个分泌素家族（包括子宫球蛋白和lipophilin）成员的远亲。与其他分泌素家族成员不同，乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中，该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时，检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白，在鉴定原发癌是否发生转移中起到至关重要的作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
