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Delta Opioid Receptor Rabbit pAb (bs-3624R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-3624R
英文名称 Delta Opioid Receptor Rabbit pAb
中文名称 D型阿片受体抗体
别    名 delta type opioid receptor; delta type opioid receptor DOR 1; DOR 1; DOR1; mDOR; Nbor; Opioid receptor delta 1; OPRD; OPRD1; OPRD_HUMAN; delta-type opioid receptor; D-OR-1; DOR-1.  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Chicken,Dog,GuineaPig)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 41 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Delta Opioid Receptor: 81-180/372 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology with SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes.

Function:
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.

Subunit:
Interacts with GPRASP1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P41143

Gene ID:
4985

Database links:

Entrez Gene: 4985 Human

Entrez Gene: 18386 Mouse

Entrez Gene: 24613 Rat

Omim: 165195 Human

SwissProt: P41143 Human

SwissProt: P32300 Mouse

SwissProt: P33533 Rat

Unigene: 372 Human

Unigene: 10310 Rat



产品图片
Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-Delta Opioid Receptor (bs-3624R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 41 kD
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