| 产品编号 | bs-2792R |
| 英文名称 | Rabbit Anti-CRHR2 antibody |
| 中文名称 | 促肾上腺皮质释放激素受体2抗体 |
| 别 名 | Corticotropin releasing hormone receptor 2; Corticotropin Releasing Factor Receptor 2; Corticotropin-releasing hormone receptor 2; Corticotropin-releasing factor receptor 2; CRF 2; CRF 2R; CRF R2; CRF2; CRF2R; CRFR 2; CRFR2; CRH 2R; CRH R2; CRH2R; CRHR 2; CRHR2; CRHRⅡ. |
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Specific References (1) | bs-2792R has been referenced in 1 publications.
[IF=3.671] Fan,et al.Antitumor activity and underlying mechanism of Sargassum fusiforme polysaccharides in CNE-bearing mice.(2018) International Journal of Biological Macromolecules. 112:516-522. Other ; Mouse.
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| 研究领域 | 免疫学 神经生物学 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
| 产品应用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 43 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CRHR2: 51-150/411 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] Function: This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Interacts (via N-terminal extracellular domain) with CRF, UCN, UCN2 and UCN3. Has highest affinity for UCN, and considerably lower affinity for CRF, UNC2 and UCN3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. SWISS: Q13324 Gene ID: 1395 Database links: Entrez Gene: 1395 Human Entrez Gene: 12922 Mouse Omim: 602034 Human SwissProt: Q13324 Human SwissProt: Q60748 Mouse Unigene: 546246 Human Unigene: 236081 Mouse Unigene: 10023 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
