| 产品编号 | bs-2644R |
| 英文名称 | KIR2DS4/CD158i |
| 中文名称 | NK细胞抑制性受体2DS4抗体 |
| 别 名 | Killer cell immunoglobulin-like receptor 2DS4; CD158 antigen like family member I; CD158I; CD158i antigen; CL 17; CL 39; CL17; CL39; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 4; Killer inhibitory receptor 4 1 2; KIR antigen 2DS4; KIR1D; KIR412; KKA3; MGC120019; MGC125315; MGC125317; MHC class I NK cell receptor; Natural killer associated transcript 8; Natural killer cell inhibitory receptor; NKAT 8; NKAT8; P58 natural killer cell receptor clone CL 39; P58 natural killer cell receptor clone CL39; p58 NK receptor; KI2S4_HUMAN. |
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Specific References (1) | bs-2644R has been referenced in 1 publications.
[IF=2.38] Mozer-Lisewska, Iwona, et al. "Detection and Significance of Cytotoxic Cell Subsets in Biopsies of HCV-Infected Human Livers." Archivum immunologiae et therapiae experimentalis (2013): 1-8. Human.
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| 研究领域 | 细胞生物 免疫学 自然杀伤细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 31kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD158i: 221-290/290 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family. KIR2DS4 is a receptor on natural killer (NK) cells for HLA C alleles. It does not inhibit the activity of NK cells. Function: Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Belongs to the immunoglobulin superfamily. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. SWISS: P43632 Gene ID: 3809 Database links: Entrez Gene: 3809 Human Omim: 604955 Human SwissProt: P43632 Human Unigene: 654608 Human |
| 产品图片 |
Sample:
HL-60 Cell (Human) Lysate at 30 ug Primary: Anti-KIR2DS4'CD158i (bs-2644R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 48 kD |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
