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CXCL3 Rabbit pAb (bs-2547R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-2547R
英文名称 CXCL3 Rabbit pAb
中文名称 生长调节致癌基因gamma/GROγ抗体
别    名 CXCL3_HUMAN; C-X-C motif chemokine 3; GRO-gamma(1-73); Growth-regulated protein gamma(GRO-gamma); Macrophage inflammatory protein 2-beta(MIP2-beta); GRO-gamma(5-73); GRO3; GROG; SCYB3; MIP2B; MIP-2b; CINC-2b;  GROγ; GRO-γ; GRO γ.
Specific References  (4)     |     bs-2547R has been referenced in 4 publications.
[IF=6.166] Sugandha Saxena. et al. Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma. Am J Cancer Res. 2022; 12(1): 68–90  IHC ;  Mouse,Human.  
[IF=3.762] Wu L et al. Interleukin17–CXCR2 axis facilitates breast cancer progression by up-regulating neutrophil recruitment. Am J Pathol. 2019 Oct 22. pii: S0002-9440(19)30768-0.  IHC-P ;  Mouse.  
[IF=3.53] Gui S, Ni S, Jia J, Gong Y, Gao L, et al. (2014) Inconformity of CXCL3 Plasma Level and Placenta Expression in Preeclampsia and Its Effect on Trophoblast Viability and Invasion. PLoS ONE 9(12): e114408.  IHC-P ;  Human.  
[IF=2.766] Gui et al. Inconformity of CXCL3 plasma level and placenta expression in preeclampsia and its effect on trophoblast viability and invasion. (2014) PLoS.One. 9:e114408  IHC ;  Human.  
研究领域 肿瘤  免疫学  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 12 kDa
检测分子量
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXCL3: 35-107/107 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Growth Regulated Protein gamma (GRO gamma) is a cytokine that may play a role in inflammation and affects endothelial cells in an autocrine fashion. It belongs to the intercrine alpha family (small cytokine c-x-c) (chemokine cxc).

Function:
Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.

Subcellular Location:
Secreted.

Post-translational modifications:
N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

SWISS:
P19876

Gene ID:
2921

Database links:

Entrez Gene: 2921 Human

Omim: 139111 Human

SwissProt: P19876 Human

Unigene: 89690 Human



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