产品编号 | bs-2408R |
英文名称 | alpha Internexin Rabbit pAb |
中文名称 | α-中连蛋白抗体 |
别 名 | a-Internexin; alpha-Internexin; alpha-Internexin; 66 kDa neurofilament protein; alpha Inx; INA; Internexin neuronal intermediate filament protein alpha; MGC12702; NEF 5; NEF5; Neurofilament 5(66kD); Neurofilament 66; Neurofilament 66 tax binding protein; NF 66; NF66; NF-66; TXBP 1; TXBP1; AINX_HUMAN; alpha-Inx; Neurofilament-66. |
研究领域 | 神经生物学 干细胞 细胞粘附分子 细胞骨架 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human (predicted: Mouse,Rat,Pig,Cow,Dog,Horse) |
产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 55 kDa |
检测分子量 | |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NF-66: 251-350/499 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
eurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009] Function: Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges. Subcellular Location: Cytoplasmic. Tissue Specificity: Found predominantly in adult CNS. Post-translational modifications: O-glycosylated (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the intermediate filament family. SWISS: Q16352 Gene ID: 9118 Database links: Entrez Gene: 9118 Human Entrez Gene: 226180 Mouse Omim: 605338 Human SwissProt: Q16352 Human SwissProt: P46660 Mouse Unigene: 500916 Human Unigene: 276251 Mouse Unigene: 88941 Rat |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |