产品中心-北京博奥森生物技术有限公司

首页 > 产品中心 > 一抗 > 产品信息

Rabbit Anti-CALCRL antibody (bs-1860R)

订购热线：400-901-9800

订购邮箱：sales@bioss.com.cn

订购QQ： 400-901-9800

技术支持：techsupport@bioss.com.cn

说明书： 50ul 100ul 200ul

50ul/1180.00元

购买

100ul/1980.00元

购买

200ul/2800.00元

购买

大包装/询价

产品编号	bs-1860R
英文名称	Rabbit Anti-CALCRL antibody
中文名称	降钙素基因相关肽1型受体抗体
别名	CGRPR; CRLR; calcitonin receptor like precursor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; CGRP type 1 receptor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; Calcitonin Receptor Like Receptor; CGRP type 1 receptor; CALRL_HUMAN.
	Specific References (13) \| bs-1860R has been referenced in 13 publications. [IF=13.567] Baranowsky, Anke. et al. Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment. Bone Res. 2022 Jan;10(1):1-15 IF ; Mouse. PubMed:35087025 [IF=6.6] Romina Mancinelli. et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. CELLS-BASEL. 2022 Jan;11(9):1591 IHC ; Mouse. PubMed:35563897 [IF=6.116] E.R. Moore. et al. CGRP and Shh Mediate the Dental Pulp Cell Response to Neuron Stimulation:. J DENT RES. 0;(): IHC ; Mouse. PubMed:35403480 [IF=5.736] Jessika Appelt. et al. The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing. Ebiomedicine. 2020 Sep;59:102970 IF,IHC ; Mouse. PubMed:32853990 [IF=5.62] Fátima Gimeno-Ferrer. et al. From spreading depolarization to epilepsy with neuroinflammation: The role of CGRP in cortex. EXP NEUROL. 2022 Oct;356:114152 IF ; Rat. PubMed:35760098 [IF=4.996] Jana, Barbara. et al. Involvement of the calcitonin gene-related peptide system in the modulation of inflamed uterus contractile function in pigs. SCI REP-UK. 2022 Nov;12(1):1-14 WB ; Pig. PubMed:36352250 [IF=4.6] Toriyama, Yuichi, et al. "Pathophysiological Function of Endogenous Calcitonin Gene–Related Peptide in Ocular Vascular Diseases." The American Journal of Pathology (2015). Mouse. PubMed:25857228 [IF=4.36] Muschter D et al. Sensory neuropeptides are required for bone and cartilage homeostasis in a murine destabilization-induced osteoarthritis model. Bone. 2020 Jan 8;133:115181. IHC-P ; Mouse. PubMed:31926346 [IF=4.225] Hou K et al. Role of Calcitonin Gene-Related Peptide in Nociceptive Modulationin Anterior Cingulate Cortex of Naïve Rats and Rats With Inflammatory Pain. Front Pharmacol. 2020 Jun 26;11:928. WB ; Rat. PubMed:32670060 [IF=3.616] Shengcai Gu. et al. Interfering with CALCRL expression inhibits glioma proliferation, promotes apoptosis, and predicts prognosis in low-grade gliomas. ANN TRANSL MED. 2022 Dec;10(23):1277 IHC ; Human. PubMed:36618798 [IF=3.352] Laixi Luo. et al. Calcitonin gene-related peptide and its receptor plays important role in nociceptive regulation in the arcuate nucleus of hypothalamus of rats with inflammatory pain. BEHAV BRAIN RES. 2023 Feb;:114351 WB ; Rat. PubMed:36804439 [IF=3.347] Lin-Lin Wang. et al. Role of calcitonin gene-related peptide in pain regulation in the parabrachial nucleus of naive rats and rats with neuropathic pain. Toxicol Appl Pharm. 2021 Mar;414:115428 Rat. PubMed:33524449 [IF=2.605] Pauza AG et al. Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease. (2018) Autonomic Neuroscience.Sep 18. pii: S1566-0702(18)30176-0 IF ; Human. PubMed:30274796
研究领域	细胞生物免疫学神经生物学信号转导 G蛋白偶联受体
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse (predicted: Human,Rat)
产品应用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理论分子量	50 kDa
检测分子量
细胞定位	细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human CGRPR1: 281-380/461 <Cytoplasmic>
亚型	IgG
纯化方法	affinity purified by Protein A
缓冲液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
产品介绍	CRLR is a receptor for calcitonin gene related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries. Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in the lung and heart. Similarity: Belongs to the G-protein coupled receptor 2 family. SWISS: Q16602 Gene ID: 10203 Database links: Entrez Gene: 10203 Human Entrez Gene: 54598 Mouse Entrez Gene: 397172 Pig Entrez Gene: 25029 Rat Entrez Gene: 527140 Cow Omim: 114190 Human SwissProt: Q16602 Human SwissProt: Q9R1W5 Mouse SwissProt: Q8WN93 Pig SwissProt: Q63118 Rat Unigene: 470882 Human Unigene: 11202 Rat
产品图片	Sample: Lane 1: Mouse Kidney tissue lysates Lane 2: Mouse Heart tissue lysates Primary: Anti-CALCRL (bs-1860R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa Sample: Lane 1: Rat Lung tissue lysates Primary: Anti-CALCRL (bs-1860R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kDa Observed band size: 53 kDa

	免疫组化常用试剂
	免疫印迹常用试剂
	各种标记二抗

	1、抗体溶解方法
	2、抗体修复方式
	3、常用试剂的配制
	4、免疫组化操作步骤
	5、免疫组化问题解答
	6、Western Blotting 操作步骤
	7、Western Blotting 问题解答
	8、关于肽链的设计
	9、多肽的溶解与保存
	10、酶标抗体效价测定程序

	AbBy Fluor 350 标记
	AbBy Fluor 488 标记
	AbBy Fluor 555 标记
	AbBy Fluor 594 标记
	AbBy Fluor 647 标记
	AP 标记
	APC 标记
	Biotin 标记
	Cy3 标记
	Cy5 标记
	Cy5.5 标记
	Cy7 标记
	FITC 标记
	Gold 标记
	HRP 标记
	PE 标记
	PE-Cy3 标记
	PE-CY5 标记
	PE-CY5.5 标记
	PE-CY7 标记
	RBITC 标记