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VPS18 Rabbit pAb (bs-1953R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-1953R
英文名称 VPS18 Rabbit pAb
中文名称 空泡分选蛋白18抗体
别    名 vacuolar protein sorting protein 18; PEP3; VPS18; KIAA1475; hVPS18; Vacuolar protein sorting 18; Vacuolar protein sorting-associated protein 18; vps18; VPS18_HUMAN.  
研究领域 细胞生物  免疫学  发育生物学  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 107 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS18: 701-800/973 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

Subunit:
Interacts with HOOK1. Part of a large heterooligomeric complex together with VPS11, VPS16 and VPS33A. Interacts with STX7.

Subcellular Location:
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.

Tissue Specificity:
Ubiquitous. Expression was highest in heart and low in lung.

Similarity:
Belongs to the VPS18 family.
Contains 1 clathrin repeat.
Contains 1 RING-type zinc finger.

SWISS:
Q9P253

Gene ID:
57617

Database links:

Entrez Gene: 57617 Human

Entrez Gene: 228545 Mouse

Entrez Gene: 296083 Rat

Omim: 608551 Human

SwissProt: Q9P253 Human

SwissProt: Q8R307 Mouse

Unigene: 23876 Human

Unigene: 294761 Mouse



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