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Maspin Rabbit pAb (bs-0792R)  
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50ul/1180.00元
100ul/1980.00元
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产品编号 bs-0792R
英文名称 Maspin Rabbit pAb
中文名称 抑癌基因抗体
别    名 mammary serine proteinase inhibitor; Maspin; Ovalbumin; PI-5; PI5; Protease inhibitor 5; Serine(or cysteine) peptidase inhibitor, clade B, member 5; Serpin B5; serpin peptidase inhibitor; Serpin peptidase inhibitor, clade B(ovalbumin), member 5; SERPINB5; SPB5_HUMAN; Spi5; Spi7.  
Specific References  (1)     |     bs-0792R has been referenced in 1 publications.
[IF=1.48] Sun, Pengming, et al. "Expression patterns of maspin and mutant p53 are associated with the development of gestational trophoblastic neoplasia."Oncology Letters (2016).  IHC-P ;  Human.  
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,Rat (predicted: Human,Sheep,Horse)
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 42 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Maspin: 301-375/375 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The Maspin protein is a sour depressant of nenzyme of a kind of silk ammonia that represses the tumor, is the sour depressant of protei nenzyme one member within super household of the silk ammonia, it is in repress the tumor growth and transfer exertive certain function.

Function:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Subunit:
Interacts with IRF6.

Subcellular Location:
Secreted, extracellular space.

Tissue Specificity:
Normal mammary epithelial cells.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

SWISS:
P36952

Gene ID:
5268

Database links:

Entrez Gene: 5268 Human

Entrez Gene: 20724 Mouse

Entrez Gene: 116589 Rat

Omim: 154790 Human

SwissProt: P36952 Human

SwissProt: P70124 Mouse

SwissProt: P70564 Rat

Unigene: 55279 Human

Unigene: 268618 Mouse

Unigene: 25752 Rat



Maspin蛋白是一种抑制肿瘤的丝氨酸蛋白酶抑制剂, 是丝氨酸蛋白酶抑制剂超家族中的一员,它在抑制肿瘤生长和转移中发挥一定作用。
产品图片
Sample: Lane 1: Mouse Skin Lysates Lane 2: Rat Skin Lysates Primary: Anti-Maspin (bs-0792R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42kDa Observed band size: 42kDa
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