| 产品编号 | bs-0784R |
| 英文名称 | Rabbit Anti-IFNB1 antibody |
| 中文名称 | 干扰素β抗体 |
| 别 名 | Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFN-Beta; IFNB 1; IFNB; Interferon beta 1 fibroblast; Interferon beta precursor; IFNB_HUMAN. IFN-β; IFN β; β-IFN; IFB; β IFN; βIFN. |
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Specific References (5) | bs-0784R has been referenced in 5 publications.
[IF=14.588] Hou L et al. Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity. ACS Nano. 2020 Apr 28;14(4):3927-3940.
[IF=13.273] Weihong Guo. et al. Improved immunotherapy for gastric cancer by nanocomposites with capability of triggering Dual-Damage of Nuclear/Mitochondrial DNA and cGAS/STING-Mediated innate immunity. CHEM ENG J. 2022 Sep;443:136428 WB ; Mouse.
[IF=5.195] Yuxi Liang. et al. The crude extract from the flowers of Trollius chinensis Bunge exerts anti-influenza virus effects through modulation of the TLR3 signaling pathway. J ETHNOPHARMACOL. 2023 Jan;300:115743 WB ; Mouse.
[IF=4.432] Pengfei Cheng. et al. A3 adenosine receptor agonist IB-MECA reverses chronic cerebral ischemia-induced inhibitory avoidance memory deficit. Eur J Pharmacol. 2022 Apr;921:174874 WB ; Mouse.
[IF=1.984] Liang Y et al. Astragalus Membranaceus Treatment Protects Raw264. 7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway. Evid Based Complement Alternat Med. 2019 Dec 31;2019:2971604. WB ; Mouse&canine.
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| 研究领域 | 肿瘤 免疫学 细菌及病毒 干扰素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse (predicted: Rat) |
| 产品应用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 20kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse IFNB1: 101-184/184 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015] Function: Has antiviral, antibacterial and anticancer activities. Subunit: Monomer. Subcellular Location: Secreted. Similarity: Belongs to the alpha/beta interferon family. SWISS: P01575 Gene ID: 15977 Database links: Entrez Gene: 15977 Mouse SwissProt: P01575 Mouse Unigene: 1245 Mouse β型干扰素(Interferon-β,IFN-β)是主要由成纤维细胞产生的细胞因子,属于单一基因编码产生的蛋白质,可通过干扰病毒RNA或DNA复制而抑制病毒生长,并可显著增强NK细胞杀伤活性,通过促进MHCⅠ类分子表达而增强CTL对病毒感染细胞的识别和杀伤作用. |
| 产品图片 |
Sample:
Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 ug
Lane 2: THP-1 (Human) Cell Lysate at 30 ug
Primary: Anti-IFN beta (bs-0784R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kD
Observed band size: 24 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
