| 产品编号 | bs-42429P |
| 英文名称 | Recombinant Human SMARCA4 Protein，N-GST & C-His |
| 中文名称 | 重组人抑癌基因SNF2β蛋白 |
| 别 名 | SMCA4_HUMAN; Transcription activator BRG1; EC:3.6.4.- ; ATP-dependent helicase SMARCA4; BRG1-associated factor 190A (BAF190A); Mitotic growth and transcription activator; Protein BRG-1; Protein brahma homolog 1; BAF190A; BRG1; SNF2B; SNF2L4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; OTSC12; SNF2LB; hSNF2b; SNF2-beta; |
| 克 隆 号 | |
| 理论分子量 | 37.4 kDa |
| 检测分子量 | |
| 性 状 | Liquid |
| 浓 度 | >1mg/ml |
| 纯 度 | >90% as determined by SDS-PAGE |
| 缓 冲 液 | 50mM Tris-Hcl (pH=8.0) with 10mM GSH and 1mM PMSF |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Alternatively spliced transcripts have been found for this gene, but their full-length natures have not been determined. SWISS: P51532 Gene ID: 6597 转录调节因子（Transcriptin Regulators） SMARCA4是一种新的抑癌基因，已在许多肿瘤的研究中发现它是一种重要的抑癌基因，很多肿瘤的发生与其功能失活或出现基因突变、缺失相关联。 |
| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
