产品编号 |
bs-42428P |
英文名称 |
Recombinant human METTL11A protein, N-His
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中文名称 |
重组人甲基化样蛋白11 |
别 名 |
Methyltransferase like 11A; Methyltransferase-like protein 11A; Mettl11a; N-terminal RCC1 methyltransferase; NRMT; NTM1A; NTM1A_HUMAN; NTMT1; X-Pro-Lys N-terminal protein methyltransferase 1A; AD 003; Alpha N-terminal protein methyltransferase 1A; C9orf32; Chromosome 9 open reading frame 32. |
理论分子量 |
35kDa |
性 状 |
Liquid |
浓 度 |
>1mg/ml |
缓 冲 液 |
20mM Tris-Hcl (pH=8.0) with 8M Urea |
保存条件 |
>90% as determined by SDS-PAGE |
产品介绍 |
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala, Pro or Ser residue in the [Ala/Pro/Ser]-Pro-Lys motif. Mediates the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation.
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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