| 产品编号 |
bs-42453P |
| 英文名称 |
Recombinant human Calreticulin protein, C-His
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| 中文名称 |
重组人钙网蛋白 |
| 别 名 |
Autoantigen RO; CALR; CALR protein; CALR_HUMAN; cC1qR; CRP55; CRTC; Endoplasmic reticulum resident protein 60; ERp60; grp60; HACBP; RO; Sicca syndrome antigen A; SSA. |
| 理论分子量 |
48.5kDa |
| 性 状 |
Liquid |
| 浓 度 |
>1mg/ml |
| 缓 冲 液 |
20mM Tris-Hcl (pH=8.0) with 150mM NaCL |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 产品介绍 |
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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