产品编号 |
bs-42433P |
英文名称 |
Recombinant human CHAT protein, N-His
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中文名称 |
重组人ChAT胆碱乙酰转移酶蛋白 |
别 名 |
Choline O acetyltransferase; Choline O acetyltransferase; Acetyl CoA choline O acetyltransferase; Acetyl CoA:choline O acetyltransferase; ChAT; CHOACTase; Choline acetylase; choline acetyltransferase; CMS1A; CMS1A2; EC 2.3.1.6; OTTHUMP00000019583; OTTHUMP00000019584; CLAT_HUMAN. |
理论分子量 |
42.8kDa |
性 状 |
Liquid |
浓 度 |
>1mg/ml |
缓 冲 液 |
20mM Tris-Hcl (pH=8.0) with 8M Urea |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
产品介绍 |
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010].
胆碱乙酰转移酶(Choline Acetyltransferase,ChAT 又称为:choline O-Acetyltransferase ,CHOACTase;)是催化胆碱和乙酰辅酶A转变为乙酰和辅酶A的一种酶。ChAT有M,S,R三个亚型,此抗体与三个亚型都反应。
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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